Not really a question without a question mark, but I’ll answer it with yes.
Missing question mark, but assuming question; yes, but you’d first need to cut it up into more workable pieces. Technically, yes, but I wouldn’t use it for that. I’d rather use the table saw to cut it up into manageable pieces first.
Yes, the CNC router requires training. Aside from a minimal training for the CNC router, metal CNC training carries over though, but ask @Lukeo or #woodworking on Slack.
1/4" plywood cuts fairly well on the laser. Ideally birch or something else with low amount of glue.
Typical settings would be full power (i.e. 60%) @ 15 mm/s speed. You’ll want to do a test using your material.
The laser bed is 800 mm x 1000 mm - you’ll need to cut down a 24" x 48" before you put it on the laser.
There are quite a few free services for generating plans for laser cut boxes. For example: